Thanos D Halazonetis: search on Z-Library

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1

Genomic instability — an evolving hallmark of cancer

Negrini, Simona, Gorgoulis, Vassilis G., Halazonetis, Thanos D.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2010

Language:

english

File:

PDF, 495 KB

english, 2010

2

Determination of the c-MYC DNA-Binding Site

Thanos D. Halazonetis and Amany N. Kandil

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.24 MB

english, 1991

3

10.1038/542

Waterman, Matthew J. F., Stavridi, Elena S., Waterman, Jennifer L. F., Halazonetis, Thanos D.

Journal:

Nature Genetics

Year:

1998

Language:

english

File:

PDF, 258 KB

english, 1998

4

An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity

Petty, Tom J, Emamzadah, Soheila, Costantino, Lorenzo, Petkova, Irina, Stavridi, Elena S, Saven, Jeffery G, Vauthey, Eric, Halazonetis, Thanos D

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 1.42 MB

english, 2011

5

Acetylation of p53 Activates Transcription through Recruitment of Coactivators/Histone Acetyltransferases

Nickolai A. Barlev, Lin Liu, Nabil H. Chehab, Kyle Mansfield, Kimberly G. Harris, Thanos D. Halazonetis, Shelley L. Berger

Journal:

Year:

2001

Language:

english

File:

PDF, 529 KB

english, 2001

6

Crystal Structure of the FHA Domain of the Chfr Mitotic Checkpoint Protein and Its Complex with Tungstate

Elena S. Stavridi, Yentram Huyen, Ivy R. Loreto, Daniel M. Scolnick, Thanos D. Halazonetis, Nikola P. Pavletich, Philip D. Jeffrey

Journal:

Year:

2002

Language:

english

File:

PDF, 590 KB

english, 2002

7

Functional Interaction between BLM Helicase and 53BP1 in a Chk1-Mediated Pathway during S-Phase Arrest

Sagar Sengupta, Ana I. Robles, Steven P. Linke, Natasha I. Sinogeeva, Ran Zhang, Remy Pedeux, Irene M. Ward, Arkady Celeste, André Nussenzweig, Junjie Chen, Thanos D. Halazonetis and Curtis C. Harris

Journal:

The Journal of Cell Biology

Year:

2004

Language:

english

File:

PDF, 3.82 MB

english, 2004

8

Emerging common themes in regulation of PIKKs and PI3Ks

Lempiäinen, Harri, Halazonetis, Thanos D

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 582 KB

english, 2009

9

Change in oligomerization specificity of the p53 tetramerization domain by hydrophobic amino acid substitutions

Elena S. Stavridi, Loretta C. Caruso, Nabil H. Chehab, Thanos D. Halazonetis

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 530 KB

english, 1999

10

DNA Damage Signaling Recruits the RNA Polymerase II Binding Protein Che-1 to the p53 Promoter

Thanos D. Halazonetis, Jiri Bartek

Journal:

Year:

2006

Language:

english

File:

PDF, 144 KB

english, 2006

11

Ubiquitin-H2AX fusions render 53BP1 recruitment to DNA damage sites independent of RNF8 or RNF168

Kocyłowski, Maciej K, Rey, Alix J, Stewart, Grant S, Halazonetis, Thanos D

Journal:

Year:

2015

Language:

english

File:

PDF, 4.44 MB

english, 2015

12

Many faces of ATM: Eighth International Workshop on Ataxia-Telangiectasia

Thanos D. Halazonetis, Yosef Shiloh

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

1999

Language:

english

File:

PDF, 176 KB

english, 1999

13

Reversal of the DNA-Binding-Induced Loop L1 Conformational Switch in an Engineered Human p53 Protein

Emamzadah, Soheila, Tropia, Laurence, Vincenti, Ilena, Falquet, Benoît, Halazonetis, Thanos D.

Journal:

Journal of Molecular Biology

Year:

2014

Language:

english

File:

PDF, 1.09 MB

english, 2014

14

POLD3 Is Haploinsufficient for DNA Replication in Mice

Murga, Matilde, Lecona, Emilio, Kamileri, Irene, Díaz, Marcos, Lugli, Natalia, Sotiriou, Sotirios K., Anton, Marta E., Méndez, Juan, Halazonetis, Thanos D., Fernandez-Capetillo, Oscar

Journal:

Year:

2016

Language:

english

File:

PDF, 2.21 MB

english, 2016

15

Constitutively active DNA damage checkpoint pathways as the driving force for the high frequency of p53 mutations in human cancer

Thanos D. Halazonetis

Journal:

Year:

2004

Language:

english

File:

PDF, 94 KB

english, 2004

16

ATM signaling and 53BP1

Omar Zgheib, Yentram Huyen, Richard A. DiTullio Jr, Andrew Snyder, Monica Venere, Elena S. Stavridi, Thanos D. Halazonetis

Journal:

Radiotherapy and Oncology

Year:

2005

Language:

english

File:

PDF, 147 KB

english, 2005

17

Microcollimator for Micrometer-Wide Stripe Irradiation of Cells Using 20–30 keV X Rays

Pataky, Kristopher, Villanueva, Guillermo, Liani, Andre, Zgheib, Omar, Jenkins, Nathan, Halazonetis, Demetrios J., Halazonetis, Thanos D., Brugger, Juergen

Journal:

Radiation Research

Year:

2009

Language:

english

File:

PDF, 347 KB

english, 2009

18

Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23

MacPherson, David, Kim, Jungho, Kim, Teresa, Rhee, Byung Kirl, van Oostrom, Conny Th M, DiTullio, Richard A, Venere, Monica, Halazonetis, Thanos D, Bronson, Roderick, de Vries, Annemieke

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 476 KB

english, 2004

19

Studies of genomic copy number changes in human cancers reveal signatures of DNA replication stress

Aygül Dereli-Öz, Gwennaelle Versini, Thanos D. Halazonetis

Journal:

Molecular Oncology

Year:

2011

Language:

english

File:

PDF, 336 KB

english, 2011

20

Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress

Macheret, Morgane, Halazonetis, Thanos D.

Journal:

Year:

2018

Language:

english

File:

PDF, 12.36 MB

english, 2018

21

Chk2 leaves the PML depot

Venere, Monica, Mochan, Tamara A., Halazonetis, Thanos D.

Journal:

Nature Cell Biology

Year:

2002

Language:

english

File:

PDF, 212 KB

english, 2002

22

Nbs1 moving up in the world

Stavridi, Elena S., Halazonetis, Thanos D.

Journal:

Nature Cell Biology

Year:

2005

Language:

english

File:

PDF, 165 KB

english, 2005

23

The CHFR mitotic checkpoint protein delays cell cycle progression by excluding Cyclin B1 from the nucleus

Summers, Matthew K, Bothos, John, Halazonetis, Thanos D

Journal:

Year:

2005

Language:

english

File:

PDF, 258 KB

english, 2005

24

Structural Differences in the DNA Binding Domains of Human p53 and Its C. elegans Ortholog Cep-1

Yentram Huyen, Philip D Jeffrey, W.Brent Derry, Joel H Rothman, Nikola P Pavletich, Elena S Stavridi, Thanos D Halazonetis

Journal:

Year:

2004

Language:

english

File:

PDF, 522 KB

english, 2004

25

Pocket Formation 3 Years after Comprehensive Periodontal Therapy*

Halazonetis, Thanos D., Smulow, Jerome B., Donnenfeld, O. Walter, Mejias, Judith E.

Journal:

Journal of Periodontology

Year:

1985

Language:

english

File:

PDF, 4.82 MB

english, 1985

26

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

Halazonetis, Thanos D., Georgopoulos, Katia, Greenberg, Michael E., Leder, Philip

Journal:

Year:

1988

Language:

english

File:

PDF, 2.19 MB

english, 1988

27

Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2

Loforese, Giulio, Malinka, Thomas, Keogh, Adrian, Baier, Felix, Simillion, Cedric, Montani, Matteo, Halazonetis, Thanos D, Candinas, Daniel, Stroka, Deborah

Journal:

EMBO Molecular Medicine

Year:

2017

Language:

english

File:

PDF, 1.58 MB

english, 2017

28

The role of SMARCAL1 in replication fork stability and telomere maintenance

Lugli, Natalia, Sotiriou, Sotirios K., Halazonetis, Thanos D.

Journal:

Year:

2017

Language:

english

File:

PDF, 286 KB

english, 2017

29

Familial holoprosencephaly associated with a translocation breakpoint at chromosomal position 7q36

Androniki G. Hatziioannou, Celeste M. Krauss, Michael B. Lewis, Thanos D. Halazonetis

Journal:

American Journal of Medical Genetics Part A

Year:

1991

Language:

english

File:

PDF, 604 KB

english, 1991

30

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

Huyen, Yentram, Zgheib, Omar, DiTullio Jr, Richard A., Gorgoulis, Vassilis G., Zacharatos, Panayotis, Petty, Tom J., Sheston, Emily A., Mellert, Hestia S., Stavridi, Elena S., Halazonetis, Thanos D.

Journal:

Year:

2004

Language:

english

File:

PDF, 548 KB

english, 2004

31

A serine 37 mutation associated with two missense mutations at highly conserved regions of p53 affect pro-apoptotic genes expression in a T-lymphoblastoid drug resistant cell line

Cinti, Caterina, Claudio, Pier Paolo, De Luca, Antonio, Cuccurese, Monica, Howard, Candace M, D'Esposito, Maurizio, Paggi, Marco G, La Sala, Dario, Azzoni, Livio, Halazonetis, Thanos D

Journal:

Year:

2000

Language:

english

File:

PDF, 412 KB

english, 2000

32

High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing

Macheret, Morgane, Bhowmick, Rahul, Sobkowiak, Katarzyna, Padayachy, Laura, Mailler, Jonathan, Hickson, Ian D., Halazonetis, Thanos D.

Journal:

Year:

2020

File:

PDF, 3.76 MB

2020

33

Chfr defines a mitotic stress checkpoint that delays entry into metaphase

Scolnick, Daniel M., Halazonetis, Thanos D.

Journal:

Year:

2000

Language:

english

File:

PDF, 257 KB

english, 2000

34

53BP1, an activator of ATM in response to DNA damage

Tamara A. Mochan, Monica Venere, Richard A. DiTullio Jr., Thanos D. Halazonetis

Journal:

Year:

2004

Language:

english

File:

PDF, 279 KB

english, 2004

35

DNA Replication Stress as a Hallmark of Cancer

Macheret, Morgane, Halazonetis, Thanos D.

Journal:

Annual Review of Pathology Mechanisms of Disease

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

36

10.1038/5472

Waterman, Matthew J. F., Stavridi, Elena S., Waterman, Jennifer L. F., Halazonetis, Thanos D.

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 53 KB

english, 1999

37

Alterations of the p16-pRb Pathway and the Chromosome Locus 9p21–22 in Non-Small-Cell Lung Carcinomas: Relationship with p53 and MDM2 Protein Expression

Vassilis G. Gorgoulis, Panayotis Zacharatos, Athanassios Kotsinas, Triantofillos Liloglou, Aspasia Kyroudi, Marinos Veslemes, Antonios Rassidakis, Thanos D. Halazonetis, John K. Field, Christos Kittas

Journal:

The American Journal of Pathology

Year:

1998

Language:

english

File:

PDF, 1.31 MB

english, 1998

38

Phosphorylation of Ser-20 Mediates Stabilization of Human p53 in Response to DNA Damage

Nabil H. Chehab, Asra Malikzay, Elena S. Stavridi and Thanos D. Halazonetis

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.29 MB

english, 1999

39

Microcollimator for Micrometer-Wide Stripe Irradiation of Cells Using 20-30 KeV X Rays

Kristopher Pataky, Guillermo Villanueva, Andre Liani, Omar Zgheib, Nathan Jenkins, Demetrios J. Halazonetis, Thanos D. Halazonetis and Juergen Brugger

Journal:

Radiation Research

Year:

2009

Language:

english

File:

PDF, 2.26 MB

english, 2009

40

p53 Binding Protein 1 (53BP1) Is an Early Participant in the Cellular Response to DNA Double-Strand Breaks

Linda B. Schultz, Nabil H. Chehab, Asra Malikzay and Thanos D. Halazonetis

Journal:

The Journal of Cell Biology

Year:

2000

Language:

english

File:

PDF, 3.42 MB

english, 2000

41

SAHF, to senesce or not to senesce?

Kocylowski, Maciej K., Halazonetis, Thanos D.

Journal:

Year:

2011

Language:

english

File:

PDF, 861 KB

english, 2011

42

p53 Sites Acetylated In Vitro by PCAF and p300 Are Acetylated In Vivo in Response to DNA Damage

Liu, Lin, Scolnick, Daniel M., Trievel, Raymond C., Zhang, Hong Bing, Marmorstein, Ronen, Halazonetis, Thanos D., Berger, Shelley L.

Journal:

Molecular and Cellular Biology

Year:

1999

Language:

english

File:

PDF, 1.05 MB

english, 1999

43

R‐spondin 1 and noggin facilitate expansion of resident stem cells from non‐damaged gallbladders

Lugli, Natalia, Kamileri, Irene, Keogh, Adrian, Malinka, Thomas, Sarris, Michalis E, Talianidis, Iannis, Schaad, Olivier, Candinas, Daniel, Stroka, Deborah, Halazonetis, Thanos D

Journal:

Year:

2016

Language:

english

File:

PDF, 2.17 MB

english, 2016

44

Monitoring early S-phase origin firing and replication fork movement by sequencing nascent DNA from synchronized cells

Macheret, Morgane, Halazonetis, Thanos D.

Journal:

Nature Protocols

Year:

2018

Language:

english

File:

PDF, 816 KB

english, 2018

45

TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint

Cescutti, Rachele, Negrini, Simona, Kohzaki, Masaoki, Halazonetis, Thanos D

Journal:

The EMBO Journal

Year:

2010

Language:

english

File:

PDF, 1.82 MB

english, 2010

46

Structure–based rescue of common tumor–derived p53 mutants

Wieczorek, Ania M., Waterman, Jennifer L.F., Waterman, Matthew J.F., Halazonetis, Thanos D.

Journal:

Nature Medicine

Year:

1996

File:

PDF, 627 KB

1996

47

The Chfr mitotic checkpoint protein functions with Ubc13-Mms2 to form Lys63-linked polyubiquitin chains

Bothos, John, Summers, Matthew K, Venere, Monica, Scolnick, Daniel M, Halazonetis, Thanos D

Journal:

Year:

2003

Language:

english

File:

PDF, 252 KB

english, 2003

48

Involvement of a p53-Dependent Pathway in Rubella Virus-Induced Apoptosis

Klara Megyeri, Klara Berencsi, Thanos D. Halazonetis, George C. Prendergast, Giorgia Gri, Stanley A. Plotkin, Giovanni Rovera, Eva Gönczöl

Journal:

Year:

1999

Language:

english

File:

PDF, 456 KB

english, 1999

49

SCFβTrCP-Mediated Degradation of Claspin Regulates Recovery from the DNA Replication Checkpoint Response

Angelo Peschiaroli, N. Valerio Dorrello, Daniele Guardavaccaro, Monica Venere, Thanos Halazonetis, Nicholas E. Sherman, Michele Pagano

Journal:

Year:

2006

Language:

english

File:

PDF, 687 KB

english, 2006

50

Evolutionarily Conserved Regions of the Human c-myc Protein Can Be Uncoupled from Transforming Activity

Jacob Sarid, Thanos D. Halazonetis, William Murphy and Philip Leder

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 592 KB

english, 1987

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